sTim-3 alleviates liver injury via regulation of the immunity microenvironment and autophagy.
Sign Up to like & getrecommendations! Published in 2020 at "Cell death discovery"
DOI: 10.1038/s41420-020-00299-7
Abstract: Liver failure (LF) is a monocyte/macrophage-mediated liver injury that has been associated with inflammatory mediators. However, the mechanism through which monocytes/macrophages regulate LF has not been fully elucidated. In this study, we investigated the role… read more here.
Keywords: stim; liver injury; monocyte macrophage;
Editorial: Countering immune regulation: sTim‐ulating SLE disease pathogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Leukocyte Biology"
DOI: 10.1189/jlb.3ce0717-279rr
Abstract: Discussion on the role of sTim‐3 in innate and adaptive immune responses during system lupus erythematous and pathogenic diseases. read more here.
Keywords: editorial countering; regulation stim; countering immune; stim ... See more keywords
Expression of Concern: The Orai-1 and STIM-1 complex controls human dendritic cell maturation
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0231469
Abstract: The authors provided image data in support of these results. They commented that the same number of cells is represented in each lane but they did not conduct control blots (e.g. actin) to assess relative… read more here.
Keywords: control; expression concern; expression; stim ... See more keywords
Decreased expression of ADAM10 on monocytes is associated with chronic allograft dysfunction in kidney transplant recipients.
Sign Up to like & getrecommendations! Published in 2023 at "International immunopharmacology"
DOI: 10.2139/ssrn.4197799
Abstract: BACKGROUND Chronic allograft dysfunction (CAD) is a common cause of allograft loss in kidney transplant recipients (KTRs). Our previous study found that elevated serum soluble T cell immunoglobulin mucin-3 (sTim-3) was positively associated with the… read more here.
Keywords: cad; expression; mtim; allograft ... See more keywords
Safety and efficacy of electrical stimulation for lower-extremity muscle weakness in intensive care unit 2019 Novel Coronavirus patients: A phase I double-blinded randomized controlled trial
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.1017371
Abstract: Background Intensive care unit (ICU) prolonged immobilization may lead to lower-extremity muscle deconditioning among critically ill patients, particularly more accentuated in those with 2019 Novel Coronavirus (COVID-19) infection. Electrical stimulation (E-Stim) is known to improve… read more here.
Keywords: stim; safety efficacy; lower extremity; extremity muscle ... See more keywords
Increase in Serum Soluble Tim-3 Level Is Related to the Progression of Diseases After Hepatitis Virus Infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.880909
Abstract: Background Viral hepatitis is a widespread and serious infectious disease, and most patients with liver cirrhosis and hepatocellular carcinoma are prone to viral infections. T cell immunoglobulin-and mucin-domain-containing molecule-3 (Tim-3) is an immune checkpoint molecule… read more here.
Keywords: virus infection; infection; hepatitis virus; hepatitis ... See more keywords
Noninvasive detection of acute renal allograft rejection by measurement of soluble Tim-3 in urine.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.6670
Abstract: The purpose of the present study was to assess whether urinary soluble T-cell immunoglobulin and mucin domain-containing protein 3 (sTim-3) could be adopted as a novel non‑invasive biomarker for acute rejection (AR) following renal transplantation.… read more here.
Keywords: rejection; renal allograft; stim; mmol creatinine ... See more keywords