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   Articles with "stim2" as a keyword



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Orai1 inhibitor STIM2β regulates myogenesis by controlling SOCE dependent transcriptional factors

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recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-47259-5

Abstract: Store-operated Ca2+ entry (SOCE), the fundamental Ca2+ signaling mechanism in myogenesis, is mediated by stromal interaction molecule (STIM), which senses the depletion of endoplasmic reticulum Ca2+ stores and induces Ca2+ influx by activating Orai channels… read more here.

Keywords: stim2; stim2 myogenesis; function stim2; orai1 inhibitor ... See more keywords
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Stepping out of the shadow: STIM2 promotes IL-3–induced cytokine release

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recommendations! Published in 2019 at "Science Signaling"

DOI: 10.1126/scisignal.aax0210

Abstract: Basophils require the calcium sensor STIM2 to respond to the cytokine IL-3 (Yoshikawa et al., in 9 April 2019 issue). Basophils are a small population of innate immune cells, but their release of the cytokine… read more here.

Keywords: stim2; promotes induced; shadow stim2; stim2 promotes ... See more keywords
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Identification of molecular determinants that govern distinct STIM2 activation dynamics

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recommendations! Published in 2018 at "PLoS Biology"

DOI: 10.1371/journal.pbio.2006898

Abstract: The endoplasmic reticulum (ER) Ca2+ sensors stromal interaction molecule 1 (STIM1) and STIM2, which connect ER Ca2+ depletion with extracellular Ca2+ influx, are crucial for the maintenance of Ca2+ homeostasis in mammalian cells. Despite the… read more here.

Keywords: stim2; activation dynamics; stim2 activation; identification molecular ... See more keywords
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Changes in STIM isoforms expression and gender-specific alterations in Orai expression in human heart failure.

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recommendations! Published in 2019 at "Physiological research"

DOI: 10.33549/physiolres.934300

Abstract: Store-operated calcium entry (SOCE) is one of regulatory mechanisms which regulates Ca2+ cycling in the heart. SOCE alterations in pathological conditions contribute to progression of heart failure and cardiac hypertrophy by multiple signaling pathways such… read more here.

Keywords: gender specific; stim2; heart; heart failure ... See more keywords