In Esophageal Squamous Cells from Eosinophilic Esophagitis Patients, Th2 Cytokines Increase Eotaxin-3 Secretion through Effects on Intracellular Calcium and a Non-Gastric Proton Pump.
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DOI: 10.1053/j.gastro.2021.02.016
Abstract: BACKGROUND & AIMS In upper airway cells, Th2 cytokines that signal through IL-4 receptor alpha (IL4Rα) have been shown to stimulate eotaxin-3 secretion via a non-gastric proton pump (ngH+,K+ATPase). To seek novel targets for eosinophilic… read more here.
Keywords: intracellular calcium; eotaxin secretion; calcium; non gastric ... See more keywords