Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations
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DOI: 10.1038/s41598-020-69031-w
Abstract: Ferritin is an iron-binding molecule, which comprises 24 subunits, heavy (FeH) and light (FeL) subunits, suggested to have a pathogenic role by the ‘hyperferritinemic syndrome’. In this work, we tested (1) FeH and FeL in… read more here.
Keywords: stimulated macrophages; proliferation; feh stimulated; feh ... See more keywords
Neoagaro-oligosaccharide monomers inhibit inflammation in LPS-stimulated macrophages through suppression of MAPK and NF-κB pathways
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DOI: 10.1038/srep44252
Abstract: Neoagaro-oligosaccharides derived from agarose have been demonstrated to possess a variety of biological activities, such as anti-bacteria and anti-oxidative activities. In this study, we mainly explored the inhibitory effects and the mechanisms of neoagaro-oligosaccharide monomers… read more here.
Keywords: lps stimulated; stimulated macrophages; inflammation; neoagaro oligosaccharide ... See more keywords
Exosomes derived from oxLDL-stimulated macrophages induce neutrophil extracellular traps to drive atherosclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Cell Cycle"
DOI: 10.1080/15384101.2019.1654797
Abstract: ABSTRACT This study aimed to investigate the role and underlying mechanism of exosomes secreted by oxidized low-density lipoprotein (oxLDL)-stimulated macrophages in the progression of atherosclerosis (AS). Exosomes from peripheral blood of AS patients or oxLDL-treated… read more here.
Keywords: neutrophil extracellular; oxldl stimulated; stimulated macrophages; oxldl treated ... See more keywords
Abstract 4497: Delineating the effects of different levels of nitric oxide produced by "M1" stimulated macrophages on tumor rejection and response to therapy
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4497
Abstract: Nitric Oxide (NO) was historically known to be immunosuppressive in cancers by inhibiting T-cell function and endothelial activation. This is relevant however only in the aberrant, dysfunctional tumor vasculature. Recently, local low dose irradiation was… read more here.
Keywords: different levels; stimulated macrophages; tumor rejection; nitric oxide ... See more keywords
The effects of the molecular weights of hyaluronic acid on the immune responses
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DOI: 10.1186/s40824-021-00228-4
Abstract: The molecular weight of hyaluronic acid (HyA) depends on the type of organ in the body. When HyA of the desired molecular weight is implanted into the human body for regeneration of damaged tissue, it… read more here.
Keywords: molecular weights; hmw 500; lps stimulated; stimulated macrophages ... See more keywords
Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0198609
Abstract: Macrophages exhibit diverse effector phenotypes depending on the stimuli and their microenvironment. Classically activated macrophages are primed with interferon (IFN)γ and stimulated with pathogen-associated molecular patterns. They produce inflammatory mediators and inflammatory cytokines, such as… read more here.
Keywords: immune complexes; notch signaling; stimulated macrophages; presence immune ... See more keywords
Role of metabolic reprogramming in pro-inflammatory cytokine secretion from LPS or silica-activated macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.936167
Abstract: In the lungs, macrophages constitute the first line of defense against pathogens and foreign bodies and play a fundamental role in maintaining tissue homeostasis. Activated macrophages show altered immunometabolism and metabolic changes governing immune effector… read more here.
Keywords: stimulated macrophages; secretion; role metabolic; activated macrophages ... See more keywords
Exosomes derived from oxidized LDL-stimulated macrophages attenuate the growth and tube formation of endothelial cells.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2018.8380
Abstract: Oxidized low-density lipoprotein (oxLDL) has a critical role in the development of atherosclerosis. The participation of oxLDL‑stimulated macrophages has been well‑established in atherosclerosis, however the underlying mechanisms are unclear. Macrophage‑derived exosomes are actively released and… read more here.
Keywords: growth tube; stimulated macrophages; endothelial cells; tube formation ... See more keywords