Upstream stimulating factor 1 suppresses autophagy and hepatic lipid droplet catabolism by activating mTOR
Sign Up to like & getrecommendations! Published in 2018 at "Febs Letters"
DOI: 10.1002/1873-3468.13203
Abstract: Previous studies indicate that the transcription factor upstream stimulating factor 1 (USF1) is involved in the regulation of lipid and glucose metabolism. However, the role of USF1 in lipid‐induced autophagy remains unknown. Interestingly, we found… read more here.
Keywords: suppresses autophagy; stimulating factor; upstream stimulating; mtor ... See more keywords
Elevated granulocyte colony stimulating factor (CSF) causes cerebellar deficits and anxiety in a model of CSF‐1 receptor related leukodystrophy
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24310
Abstract: Colony stimulating factor (CSF) receptor‐1 (CSF‐1R)‐related leukoencephalopathy (CRL) is an adult‐onset, demyelinating and neurodegenerative disease caused by autosomal dominant mutations in CSF1R, modeled by the Csf1r+/− mouse. The expression of Csf2, encoding granulocyte‐macrophage CSF (GM‐CSF)… read more here.
Keywords: csf; csf3; csf1r mice; stimulating factor ... See more keywords
Granulocyte colony‐stimulating factor has a sex‐dependent positive effect in the maternal immune activation‐induced autism model
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10221
Abstract: The medical intervention for autism spectrum disorder (ASD) is restricted to ameliorating comorbid situations. Granulocyte colony‐stimulating factor (G‐CSF) is a growth factor that enhances the proliferation, differentiation, and survival of hematopoietic progenitor cells. In the… read more here.
Keywords: granulocyte colony; autism; maternal immune; factor ... See more keywords
Functional Secretion of Granulocyte Colony Stimulating Factor in Bacillus subtilis and Its Thermogenic Activity in Brown Adipocytes
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-019-0127-1
Abstract: Granulocyte colony-stimulating factor (G-CSF) is involved in generation of colonies hematopoietic cells by stimulation of bone marrow cells, resulting in the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils. To express and… read more here.
Keywords: stimulating factor; csf; colony stimulating; brown adipocytes ... See more keywords
B lymphocyte stimulating factor of Trachinotus ovatus (TroBLyS) promotes antibacterial immune defense
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.736437
Abstract: Abstract B lymphocyte stimulating factor (BLyS) belongs to the tumor necrosis family (TNF), which is a key cytokine in promoting the survival, proliferation, differentiation and apoptosis of B cells, and regulating the functions of T… read more here.
Keywords: trachinotus ovatus; ovatus troblys; lymphocyte stimulating; stimulating factor ... See more keywords
UNC93B1 promotes tumoral growth by controlling the secretion level of granulocyte macrophage colony-stimulating factor in human oral cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.03.172
Abstract: Unc-93 homolog B1 (UNC93B1), a transmembrane protein, is correlated with immune diseases, such as influenza, herpes simplex encephalitis, and the pathogenesis of systemic lupus erythematosus; however, the role of UNC93B1 in cancers including human oral… read more here.
Keywords: stimulating factor; level; macrophage colony; colony stimulating ... See more keywords
Granulocyte‐colony stimulating factor enhances bone fracture healing
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Biomechanics"
DOI: 10.1016/j.clinbiomech.2018.07.010
Abstract: Background: Circulating mesenchymal stem cells contribute to bone repair. Their incorporation in fracture callus is correlated to their bioavailability. In addition, Granulocyte‐colony stimulating factor induces the release of vascular and mesenchymal progenitors. We hypothesized that… read more here.
Keywords: colony stimulating; granulocyte colony; group; stimulating factor ... See more keywords
Efficiency of granulocyte colony-stimulating factor immobilized on magnetic microparticles on proliferation of NFS-60 cells
Sign Up to like & getrecommendations! Published in 2019 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2019.123580
Abstract: Abstract Magnetic particles are promising carriers for targeted drug delivery. Granulocyte colony-stimulating factor (G-CSF) is a cytokine which stimulates neutrophil proliferation process. In this study, G-CSF molecules were successfully covalently immobilized on magnetic silica gel… read more here.
Keywords: immobilized magnetic; csf; granulocyte colony; stimulating factor ... See more keywords
Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2021.113298
Abstract: Tumor-associated macrophages (TAMs) are predominantly associated with tumor growth. Colony-stimulating factor 1 receptor (CSF1R) acts as a key regulator of TAM survival and differentiation and is a molecular target for cancer therapies. Herein, novel CSF1R… read more here.
Keywords: hinge; factor receptor; colony stimulating; stimulating factor ... See more keywords
Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-01881-x
Abstract: Cocaine addiction is characterized by dysfunction in reward-related brain circuits, leading to maladaptive motivation to seek and take the drug. There are currently no clinically available pharmacotherapies to treat cocaine addiction. Through a broad screen… read more here.
Keywords: stimulating factor; csf; colony stimulating; granulocyte colony ... See more keywords
Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Data"
DOI: 10.1038/s41597-019-0015-8
Abstract: Granulocyte colony stimulating factor receptor (G-CSFR) plays an important role in the production of neutrophil granulocytes. Mutated G-CSFRs have been directly associated with two distinct malignant phenotypes in patients, e.g. acute myeloid leukemia (AML) and… read more here.
Keywords: analysis; stimulating factor; normal mutated; colony stimulating ... See more keywords