Stimulation of Hepatic Ferritinophagy Mitigates Irp2 Depletion-Induced Anemia
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DOI: 10.3390/antiox12030566
Abstract: Background: Iron regulatory proteins (IRPs) maintain cellular iron homeostasis. Due to aberrant tissue-iron distribution, Irp2-deficient mice suffer microcytic anemia and neurodegeneration, while iron overload occurs in the liver and intestine. We previously found that Irp2… read more here.
Keywords: induced anemia; iron; stimulation hepatic; iron distribution ... See more keywords