The discovery of potent immunostimulatory CpG-ODNs widely distributed in bacterial genomes
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DOI: 10.1007/s12275-020-9289-y
Abstract: Oligodeoxynucleotides containing unmethylated CpG dinucleotides (CpG-ODN) can be specifically recognized by Toll-like receptor 9 (TLR9), provoking innate immune responses. Designed according to this structural feature, many synthetic phosphorothioate CpG-ODNs successfully activate macrophages. However, it is… read more here.
Keywords: dna; dna fragments; stimulatory cpg; cpg odns ... See more keywords