Modeling the structure of the frameshift-stimulatory pseudoknot in SARS-CoV-2 reveals multiple possible conformers
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DOI: 10.1371/journal.pcbi.1008603
Abstract: The coronavirus causing the COVID-19 pandemic, SARS-CoV-2, uses −1 programmed ribosomal frameshifting (−1 PRF) to control the relative expression of viral proteins. As modulating −1 PRF can inhibit viral replication, the RNA pseudoknot stimulating −1… read more here.
Keywords: stimulatory pseudoknot; structure; pseudoknot; sars cov ... See more keywords