Bioactive modulators targeting STING adaptor in cGAS-STING pathway.
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DOI: 10.1016/j.drudis.2019.11.007
Abstract: The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING)-pathway triggers innate immune responses by recognizing cytosolic DNA. Recent studies revealed that STING adaptor associates with various diseases, and several modulators targeting STING have been identified… read more here.
Keywords: cgas; sting pathway; targeting sting; sting adaptor ... See more keywords