Targeting STING with cyclic di-GMP greatly augmented immune responses of glycopeptide cancer vaccines.
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DOI: 10.1039/c8cc04860f
Abstract: Cyclic di-GMP (CDG) was applied to MUC1 glycopeptide-based cancer vaccines with physical mixing and built-in (at 2'-OH of CDG) strategies for activating the STING pathway. CDG in both strategies behaved as a potent immunostimulant and… read more here.
Keywords: sting cyclic; cyclic gmp; targeting sting; cancer vaccines ... See more keywords