Articles with "sting ifn" as a keyword



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Protein Tyrosine Phosphatase Receptor Type D Regulates Neuropathic Pain After Nerve Injury via the STING-IFN-I Pathway

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Published in 2022 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2022.859166

Abstract: Neuropathic pain is usually caused by injury or dysfunction of the somatosensory system, and medicine is a common way of treatment. Currently, there are still no satisfactory drugs, like opioids and lidocaine, which carry a… read more here.

Keywords: protein tyrosine; ptprd; tyrosine phosphatase; neuropathic pain ... See more keywords
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The STING-IFN-β-Dependent Axis Is Markedly Low in Patients with Relapsing-Remitting Multiple Sclerosis

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21239249

Abstract: Cyclic GMP-AMP-synthase is a sensor of endogenous nucleic acids, which subsequently elicits a stimulator of interferon genes (STING)-dependent type I interferon (IFN) response defending us against viruses and other intracellular pathogens. This pathway can drive… read more here.

Keywords: dependent axis; ifn dependent; multiple sclerosis; sting ifn ... See more keywords