Abstract 5170: STING inflames NF1 malignancies for immunotherapy
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DOI: 10.1158/1538-7445.am2023-5170
Abstract: Introduction: Neurofibromatosis Type 1 (NF1) is caused by mutations in the NF1 gene that encodes neurofibromin, a RAS GTPase-Activating Protein. Inactivating NF1 mutations result in hyperactivation of RAS-mediated signaling. NF1 patients develop benign tumors on… read more here.
Keywords: cell; sting agonist; icb; sting inflames ... See more keywords