STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2118819119
Abstract: Significance It is increasingly recognized that chronic neuroinflammation is causally relevant to neurodegeneration. In Parkinson’s disease (PD), α-synuclein pathology activates inflammatory signaling that disturbs parenchymal homeostasis and disrupts neuron-glia interactions. Herein, we report that the… read more here.
Keywords: sting mediates; neuroinflammation nigrostriatal; neuroinflammation; nigrostriatal synucleinopathy ... See more keywords
Goose STING mediates IFN signaling activation against RNA viruses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.921800
Abstract: Stimulator of the interferon gene (STING) is involved in mammalian antiviral innate immunity as an interferon (IFN) activator. However, there is still a lack of clarity regarding the molecular characterization of goose STING (GoSTING) and… read more here.
Keywords: sting mediates; ifn; goose sting; gfp ... See more keywords