Activating Innate Immunity by a STING Signal Amplifier for Local and Systemic Immunotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c03509
Abstract: The number of patients who benefit from acquired immunotherapy is limited. Stimulator of interferon genes (STING) signal activation is a significant component to enhance innate immunity, which has been used to realize broad-spectrum immunotherapy. Here,… read more here.
Keywords: signal amplifier; immunotherapy; sting signal; innate immunity ... See more keywords
The cGAS-STING Pathway: A Promising Immunotherapy Target
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.795048
Abstract: With the continuous development of immunotherapy, researchers have paid more attention to the specific immune regulatory mechanisms of various immune responses in different diseases. As a novel and vital innate immune signal pathway, the cGAS-STING… read more here.
Keywords: signal pathway; immunity; sting signal; cgas sting ... See more keywords
Chicken DNA Sensing cGAS-STING Signal Pathway Mediates Broad Spectrum Antiviral Functions
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DOI: 10.3390/vaccines8030369
Abstract: The innate DNA sensing receptors are one family of pattern recognition receptors and play important roles in antiviral infections, especially DNA viral infections. Among the multiple DNA sensors, cGAS has been studied intensively and is… read more here.
Keywords: sting signal; dna; antiviral functions; cgas sting ... See more keywords