cGAS–STING signalling in cancer: striking a balance with chromosomal instability
Sign Up to like & getrecommendations! Published in 2023 at "Biochemical Society Transactions"
DOI: 10.1042/bst20220838
Abstract: Chromosomal instability (CIN) is a hallmark of cancer that drives tumour evolution. It is now recognised that CIN in cancer leads to the constitutive production of misplaced DNA in the form of micronuclei and chromatin… read more here.
Keywords: cgas sting; signalling cancer; chromosomal instability; sting signalling ... See more keywords
EPCO-21. STING PROMOTER EPIGENETIC SILENCING IN GLIOBLASTOMA
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DOI: 10.1093/neuonc/noaa215.300
Abstract: The Stimulator of interferon genes (STING) protein is a critical component of the innate immune response to pathogenic and cytosolic self DNA. The importance of STING signalling has recently been demonstrated in a number of… read more here.
Keywords: methylation; glioblastoma; sting signalling; promoter ... See more keywords