The STING1 network regulates autophagy and cell death
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-021-00613-4
Abstract: Cell death and immune response are at the core of life. In past decades, the endoplasmic reticulum (ER) protein STING1 (also known as STING or TMEM173) was found to play a fundamental role in the… read more here.
Keywords: death; network; autophagy cell; cell death ... See more keywords
UXT attenuates the CGAS-STING1 signaling by targeting STING1 for autophagic degradation
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2076192
Abstract: ABSTRACT STING1 (stimulator of interferon response cGAMP interactor 1), the pivotal adaptor protein of CGAS (cyclic GMP-AMP synthase)-STING1 signaling, is critical for type I IFN production of innate immunity. However, excessive or prolonged activation of… read more here.
Keywords: autophagic degradation; sting1; cyclic gmp; sting1 signaling ... See more keywords