UXT attenuates the CGAS-STING1 signaling by targeting STING1 for autophagic degradation
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DOI: 10.1080/15548627.2022.2076192
Abstract: ABSTRACT STING1 (stimulator of interferon response cGAMP interactor 1), the pivotal adaptor protein of CGAS (cyclic GMP-AMP synthase)-STING1 signaling, is critical for type I IFN production of innate immunity. However, excessive or prolonged activation of… read more here.
Keywords: autophagic degradation; sting1; cyclic gmp; sting1 signaling ... See more keywords