Relaxation Dynamics vs Crystallization Kinetics in the Amorphous State: The Case of Stiripentol.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00399
Abstract: With the aim of finding a correlation between the crystallization kinetics and the molecular dynamics of a substance that would allow prediction of its crystallization time as a function of temperature for a given α… read more here.
Keywords: relaxation; relaxation dynamics; crystallization; time ... See more keywords
Impact of CYP2C19 phenotypes on clinical efficacy of stiripentol in Japanese patients with Dravet syndrome.
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DOI: 10.1097/ftd.0000000000000676
Abstract: BACKGROUND Stiripentol is a strong inhibitor of CYP2C19 and CYP3A4. This study compared the effect of stiripentol on the pharmacokinetics of clobazam and N-desmethyl-clobazam (NCLB; an active metabolite of clobazam) between different CYP2C19 phenotypes. We… read more here.
Keywords: japanese patients; cyp2c19 phenotypes; patients dravet; group ... See more keywords