Cancer‐testis gene STK31 is regulated by methylation and promotes the development of pancreatic cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5472
Abstract: Pancreatic cancer (PC) is a highly invasive malignancy with extremely poor prognosis. STK31 has been identified as a cancer‐testis (CT) gene, but its function in PC has not been elucidated well. read more here.
Keywords: testis gene; pancreatic cancer; stk31; cancer ... See more keywords
Abstract 2218: The molecular mechanism underlying KRAS regulation on STK31 expression in pancreatic ductal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2218
Abstract: KRAS is frequently mutated in pancreatic ductal adenocarcinoma (PDAC). However, targeting mutant KRAS is still challenging. Kinase inhibitors are ideal targeted therapeutics for mutant KRAS-driven cancer. In our previous study, an esiRNA screening was prepared… read more here.
Keywords: kras mutant; ductal adenocarcinoma; stk31; pancreatic ductal ... See more keywords
MicroRNA-543 controls pancreatic cancer development by LINC00847-microRNA-543-STK31 axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-22-1017
Abstract: Background Pancreatic cancer (PC) is one of the most malignant cancers of the gastrointestinal tract. However, the study of targeted therapy research in PC is not very thorough. Therefore, targeted molecular markers are needed to… read more here.
Keywords: linc00847 microrna; microrna 543; pancreatic cancer; stk31 ... See more keywords