STK4 deficiency and EBV-associated lymphoproliferative disorders, emphasis on histomorphology, and review of literature
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DOI: 10.1007/s00428-021-03147-w
Abstract: Aberrations of the STK4 gene in humans result in an autosomal recessively inherited primary immunodeficiency. We identified three patients with STK4 deficiency who had presented to our hospital and reviewed their biopsy samples with the… read more here.
Keywords: ebv associated; deficiency ebv; stk4 deficiency; year old ... See more keywords
EBV Negative Lymphoma and Autoimmune Lymphoproliferative Syndrome Like Phenotype Extend the Clinical Spectrum of Primary Immunodeficiency Caused by STK4 Deficiency
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DOI: 10.3389/fimmu.2018.02400
Abstract: Serine/threonine kinase 4 (STK4) deficiency is an autosomal recessive genetic condition that leads to primary immunodeficiency (PID) typically characterized by lymphopenia, recurrent infections and Epstein Barr Virus (EBV) induced lymphoproliferation and -lymphoma. State-of-the-art treatment regimens… read more here.
Keywords: lymphoma; primary immunodeficiency; lymphoproliferative syndrome; stk4 deficiency ... See more keywords