Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy
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DOI: 10.1101/2022.03.13.484188
Abstract: TDP-43 mediates proper Stathmin-2 (STMN2) mRNA splicing, and STMN2 protein is reduced in the spinal cord of most ALS patients. To test the hypothesis that STMN2 loss contributes to ALS pathogenesis, we generated constitutive and… read more here.
Keywords: loss; stmn2; pathology; motor neuropathy ... See more keywords