Microtubules, Membranes, and Movement: New Roles for Stathmin‐2 in Axon Integrity
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25382
Abstract: Neurons establish functional connections responsible for how we perceive and react to the world around us. Communication from a neuron to its target cell occurs through a long projection called an axon. Axon distances can… read more here.
Keywords: roles stathmin; axon integrity; membranes movement; microtubules membranes ... See more keywords
Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1101/2022.03.13.484188
Abstract: TDP-43 mediates proper Stathmin-2 (STMN2) mRNA splicing, and STMN2 protein is reduced in the spinal cord of most ALS patients. To test the hypothesis that STMN2 loss contributes to ALS pathogenesis, we generated constitutive and… read more here.
Keywords: loss; stmn2; pathology; motor neuropathy ... See more keywords