Subthalamic nucleus volumes are highly consistent but decrease age‐dependently—a combined magnetic resonance imaging and stereology approach in humans
Sign Up to like & getrecommendations! Published in 2017 at "Human Brain Mapping"
DOI: 10.1002/hbm.23427
Abstract: The subthalamic nucleus (STN) is a main target structure of deep brain stimulation (DBS) in idiopathic Parkinson's disease. Nevertheless, there is an ongoing discussion regarding human STN volumes and neuron count, which could potentially have… read more here.
Keywords: stereology; age; stn; combined magnetic ... See more keywords
Chemogenetic modulation reveals distinct roles of the subthalamic nucleus and its afferents in the regulation of locomotor sensitization to amphetamine in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Psychopharmacology"
DOI: 10.1007/s00213-021-05985-7
Abstract: The subthalamic nucleus (STN) is a key node in cortico-basal-ganglia thalamic circuits, guiding behavioral output through its position as an excitatory relay of the striatal indirect pathway and its direct connections with the cortex. There… read more here.
Keywords: stn; amphetamine sensitization; sensitization; subthalamic nucleus ... See more keywords
Shoot tip necrosis of in vitro plant cultures: a reappraisal of possible causes and solutions
Sign Up to like & getrecommendations! Published in 2020 at "Planta"
DOI: 10.1007/s00425-020-03449-4
Abstract: Main conclusion Shoot tip necrosis is a physiological condition that negatively impacts the growth and development of in vitro plant shoot cultures across a wide range of species. Abstract Shoot tip necrosis is a physiological… read more here.
Keywords: plant; stn; tip necrosis; shoot tip ... See more keywords
Borders of STN determined by MRI versus the electrophysiological STN. A comparison using intraoperative CT
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-017-3432-5
Abstract: BackgroundIt is unclear which magnetic resonance imaging (MRI) sequence most accurately corresponds with the electrophysiological subthalamic nucleus (STN) obtained during microelectrode recording (MER, MER-STN). CT/MRI fusion allows for comparison between MER-STN and the STN visualized… read more here.
Keywords: electrophysiological stn; stn; mri; stn borders ... See more keywords
Targeting of the Subthalamic Nucleus in Patients with Parkinson’s Disease Undergoing Deep Brain Stimulation Surgery
Sign Up to like & getrecommendations! Published in 2021 at "Neurology and Therapy"
DOI: 10.1007/s40120-021-00233-8
Abstract: Precise stereotactic targeting of the dorsolateral motor part of the subthalamic nucleus (STN) is paramount for maximizing clinical effectiveness and preventing side effects of deep brain stimulation (DBS) in patients with advanced Parkinson’s disease. With… read more here.
Keywords: surgery; deep brain; stimulation; stn ... See more keywords
Synthesis of MUC1-derived glycopeptide bearing a novel triazole STn analog.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate research"
DOI: 10.1016/j.carres.2020.108155
Abstract: The synthesis of MUC1 glycopeptides bearing modified tumor-associated carbohydrate antigens (TACAs) represents an effective strategy to develop potential antitumor vaccines that trigger strong immune response. In this context, we present herein the multistep synthesis of… read more here.
Keywords: muc1 derived; stn; analog; synthesis muc1 ... See more keywords
Fault diagnosis of gas turbines with thermodynamic analysis restraining the interference of boundary conditions based on STN
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Mechanical Sciences"
DOI: 10.1016/j.ijmecsci.2020.106053
Abstract: Abstract Gas turbines are widely used in natural gas-fired power generation and long-distance natural gas pipelines. The complexity and diversity of boundary conditions usually have a great influence on the measurement parameters, which makes them… read more here.
Keywords: fault; boundary conditions; analysis; stn ... See more keywords
Combination targeting of subthalamic nucleus and ventral intermediate thalamic nucleus with a single trajectory in deep brain stimulation for tremor-dominant Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2020.12.022
Abstract: Deep brain stimulation (DBS) has traditionally been used to target the subthalamic nucleus (STN) or globus pallidus internus (GPi) to treat Parkinson's disease (PD) and the ventral intermediate thalamic nucleus (VIM) to treat essential tremor… read more here.
Keywords: tremor; tremor dominant; stn; parkinson disease ... See more keywords
Subthalamic stimulation, oscillatory activity and connectivity reveal functional role of STN and network mechanisms during decision making under conflict
Sign Up to like & getrecommendations! Published in 2018 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2018.01.001
Abstract: &NA; Inhibitory control is an important executive function that is necessary to suppress premature actions and to block interference from irrelevant stimuli. Current experimental studies and models highlight proactive and reactive mechanisms and claim several… read more here.
Keywords: decision; network mechanisms; network; oscillatory ... See more keywords
Loss of Hyperdirect Pathway Cortico-Subthalamic Inputs Following Degeneration of Midbrain Dopamine Neurons
Sign Up to like & getrecommendations! Published in 2017 at "Neuron"
DOI: 10.1016/j.neuron.2017.08.038
Abstract: The motor symptoms of Parkinson's disease (PD) are linked to abnormally correlated and coherent activity in the cortex and subthalamic nucleus (STN). However, in parkinsonian mice we found that cortico-STN transmission strength had diminished by… read more here.
Keywords: cortico stn; loss hyperdirect; stn; stn transmission ... See more keywords
Distinct roles of dorsal and ventral subthalamic neurons in action selection and cancellation
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DOI: 10.1016/j.neuron.2020.12.025
Abstract: The subthalamic nucleus (STN) supports action selection by inhibiting all motor programs except the desired one. Recent evidence suggests that STN can also cancel an already selected action when goals change, a key aspect of… read more here.
Keywords: stop signal; action selection; stn; selection cancellation ... See more keywords