Stolonidiol: Synthesis, Target Identification, and Mechanism for Choline Acetyltransferase Activation.
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DOI: 10.1021/jacs.7b01083
Abstract: Stolonidiol, a marine natural product, has been reported to potentiate the activity of choline acetyltransferase (ChAT), the enzyme that produces the neurotransmitter acetylcholine. Here we report the total synthesis of stolonidiol starting from (R)-(+)-limonene. To… read more here.
Keywords: synthesis; activity; stolonidiol; choline acetyltransferase ... See more keywords