Screening lncRNAs with diagnostic and prognostic value for human stomach adenocarcinoma based on machine learning and mRNA‐lncRNA co‐expression network analysis
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1512
Abstract: Stomach adenocarcinoma (STAD), is one of the most lethal malignancies around the world. The aim of this study was to find the long noncoding RNAs (lncRNAs) acting as diagnostic and prognostic biomarker of STAD. read more here.
Keywords: diagnostic prognostic; lncrnas diagnostic; screening lncrnas; stomach adenocarcinoma ... See more keywords
Identification of prognosis-related genes in the tumor microenvironment of stomach adenocarcinoma by TCGA and GEO datasets
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20200980
Abstract: Abstract Accumulating evidence has demonstrated that tumor microenvironment (TME) plays a crucial role in stomach adenocarcinoma (STAD) development, progression, prognosis and immunotherapeutic responses. How the genes in TME interact and behave is extremely crucial for… read more here.
Keywords: tcga geo; geo datasets; tumor microenvironment; tumor ... See more keywords
LncRNA POU6F2-AS2 contributes to malignant phenotypes and paclitaxel resistance by promoting SKP2 expression in stomach adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chemotherapy"
DOI: 10.1080/1120009x.2023.2177807
Abstract: This study aimed to investigate the role and mechanism of POU6F2-AS2 in the development of gastric cancer. POU6F2-AS2 expression was considerably higher in clinical stomach adenocarcinoma (STAD) tissues and gastric cancer cell lines (MKN-28 and… read more here.
Keywords: stomach adenocarcinoma; pou6f2 as2; expression; gastric cancer ... See more keywords
Multiple bioinformatics analysis identifies IGFBP1 as associated with the prognosis of stomach adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033346
Abstract: This study aimed to screen the hub gene for predicting the prognosis of patients with stomach adenocarcinoma (STAD). The RNA-sequencing expression data and clinical data of STAD were collected from the cancer genome atlas. The… read more here.
Keywords: prognosis; bioinformatics analysis; stomach adenocarcinoma; multiple bioinformatics ... See more keywords
Ferroptosis‐related gene NOX4, CHAC1 and HIF1A are valid biomarkers for stomach adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17171
Abstract: Ferroptosis is a regulated cell death nexus linking metabolism, redox biology and diseases including cancer. The aim of the present study was to identify a ferroptosis‐related gene prognostic signature for stomach adenocarcinoma (STAD) by systematic… read more here.
Keywords: hif1a; stomach adenocarcinoma; ferroptosis related; ferroptosis ... See more keywords
Systemic chemotherapy for gastro-oesophagogastric junction adenocarcinoma and stomach adenocarcinoma in a metastatic setting
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DOI: 10.1136/esmoopen-2020-000802
Abstract: Gastro-oesophageal (GE) cancers are a heterogeneous disease that traditionally have been approached as a monolith. Data regarding the benefit of systemic chemotherapy among the anatomical, histological and molecular subgroups of GE cancers are sparse. The… read more here.
Keywords: systemic chemotherapy; oesophagogastric junction; chemotherapy; junction adenocarcinoma ... See more keywords
Integrated characterisation of cancer genes identifies key molecular biomarkers in stomach adenocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2019-206400
Abstract: Aims Gastric cancer is one of the leading causes for cancer mortality. Recent studies have defined the landscape of genomic alterations of gastric cancer and their association with clinical outcomes. However, the pathogenesis of gastric… read more here.
Keywords: cancer genes; driver genes; values cases; gastric cancer ... See more keywords
JAK3 and TYK2 Serve as Prognostic Biomarkers and Are Associated with Immune Infiltration in Stomach Adenocarcinoma
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DOI: 10.1155/2020/7973568
Abstract: Background Stomach adenocarcinoma (STAD) is one of the most common malignant tumors. The Janus kinases (JAKs) play a significant part in cellular biological process, inflammation, and immunity. The roles of JAKs in STAD are still… read more here.
Keywords: jak3 tyk2; immune infiltration; stad; stomach adenocarcinoma ... See more keywords
Integrated Analyses of m6A Regulator-Based Signature on Its Clinical Application and Immunogenomic Landscape in Stomach Adenocarcinoma
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DOI: 10.1155/2022/2053719
Abstract: Background The whole tumor microenvironment (TME) infiltration features monitored by integrated roles of different RNA N6-methyladenosine (m6A) regulators remain elusive. Our study is aimed at exploring the association between m6A modification patterns, TME cell-infiltrating levels,… read more here.
Keywords: infiltration; cell; stomach adenocarcinoma; analyses m6a ... See more keywords
The Value of m5C-Related lncRNAs in the Prognostic Assessment and Immunotherapy of Stomach Adenocarcinoma
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DOI: 10.1155/2022/2747799
Abstract: Long noncoding RNAs (lncRNAs) are closely associated with a variety of tumors, including stomach adenocarcinoma (STAD). However, the role of 5-methylcytosine- (m5C-) related lncRNAs in STAD is still uncertain. This study investigated the value of… read more here.
Keywords: immunotherapy; stomach adenocarcinoma; m5c related; related lncrnas ... See more keywords
Comprehensive Analysis of the Immune Implication of AKAP12 in Stomach Adenocarcinoma
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DOI: 10.1155/2022/3445230
Abstract: A kinase anchor protein 12 (AKAP12) as a tumor suppressor in various cancers has been extensively studied and confirmed. However, its immune implication in stomach adenocarcinoma (STAD) remains uncertain. Here, using The Cancer Genome Atlas… read more here.
Keywords: tumor; immune implication; stomach adenocarcinoma; gene ... See more keywords