Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity
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DOI: 10.1038/nn.4454
Abstract: The skin is equipped with specialized mechanoreceptors that allow the perception of the slightest brush. Indeed, some mechanoreceptors can detect even nanometer-scale movements. Movement is transformed into electrical signals via the gating of mechanically activated… read more here.
Keywords: stoml3 oligomerization; small molecule; mechanical hypersensitivity;