Over-accrual in Bayesian adaptive trials with continuous futility stopping.
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DOI: 10.1177/17407745231154685
Abstract: Background: We explore frequentist operating characteristics of a Bayesian adaptive design that allows continuous early stopping for futility. In particular, we focus on the power versus sample size relationship when more patients are accrued than… read more here.
Keywords: stopping futility; bayesian adaptive; futility; adaptive trials ... See more keywords