The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
Sign Up to like & getrecommendations! Published in 2019 at "Nature Nanotechnology"
DOI: 10.1038/s41565-019-0591-y
Abstract: The regulatory approval of Onpattro, a lipid nanoparticle-based short interfering RNA drug for the treatment of polyneuropathies induced by hereditary transthyretin amyloidosis, paves the way for clinical development of many nucleic acid-based therapies enabled by… read more here.
Keywords: acid based; onpattro story; clinical translation; story clinical ... See more keywords
Evolving Story of Clinical Trials in Hypertrophic Cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2018 at "Circulation. Heart failure"
DOI: 10.1161/circheartfailure.117.004572
Abstract: See Article by Olivotto et al > Our greatest glory is not in never falling, but in rising every time we fall. > > —Attributed to Confucius Thousands of papers on hypertrophic cardiomyopathy have been… read more here.
Keywords: hypertrophic cardiomyopathy; heart failure; evolving story; clinical trials ... See more keywords