Stox1 induced the proliferation and cell cycle arrest in pulmonary artery smooth muscle cells via AKT signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2019.106568
Abstract: BACKGROUND Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by the vascular remodeling that also involves proliferation and migration of pulmonary artery smooth muscle cells (PASMCs). Overexpression of Storkhead box (STOX1) regulates genes involved… read more here.
Keywords: proliferation; smooth muscle; artery smooth; pulmonary artery ... See more keywords
STOX1 promotor region -922 Tâ>âC polymorphism is associated with Early-Onset preeclampsia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2022.2141612
Abstract: Abstract Preeclampsia (PE), affecting 5â8% of pregnancies, is a common pregnancy disease that has harmful effects on mother and foetus. It has been found that the STOX1 (Storkhead Box 1), which is a transcription factor,… read more here.
Keywords: gene; stox1; polymorphism; early onset ... See more keywords
Functional Evaluation of STOX1 (STORKHEAD-BOX PROTEIN 1) in Placentation, Preeclampsia, and Preterm Birth.
Sign Up to like & getrecommendations! Published in 2020 at "Hypertension"
DOI: 10.1161/hypertensionaha.120.15619
Abstract: Revaluation of the association of the STOX1 (STORKHEAD_BOX1 PROTEIN 1) transcription factor mutation (Y153H, C allele) with the early utero-vascular origins of placental pathology is warranted. To investigate if placental STOX1 Y153H genotype affects utero-vascular… read more here.
Keywords: y153h; birth; preeclampsia; stox1 ... See more keywords