Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis
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DOI: 10.1016/j.bone.2017.07.028
Abstract: Osteoarthritis (OA), affecting joints and bone, causes physical gait disability with huge socio-economic burden; treatment remains palliative. Roles for antioxidants in protecting against such chronic disorders have been examined previously. Sulforaphane is a naturally occurring… read more here.
Keywords: ort; osteoarthritis; str ort; mice ... See more keywords
Sexually dimorphic tibia shape is linked to natural osteoarthritis in STR/Ort mice
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DOI: 10.1016/j.joca.2018.03.008
Abstract: Summary Objectives Human osteoarthritis (OA) is detected only at late stages. Male STR/Ort mice develop knee OA spontaneously with known longitudinal trajectory, offering scope to identify OA predisposing factors. We exploit the lack of overt… read more here.
Keywords: ort mice; ort; cba; str ort ... See more keywords