STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract development
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DOI: 10.1093/cvr/cvad010
Abstract: Abstract Aims Retinoic acid (RA) signalling is essential for heart development, and dysregulation of the RA signalling can cause several types of cardiac outflow tract (OFT) defects, the most frequent congenital heart disease (CHD) in… read more here.
Keywords: development; human embryonic; outflow tract; stra6 ... See more keywords
STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrinology"
DOI: 10.1210/endocr/bqac215
Abstract: BACKGROUND Metastasis has emerged to be an important cause for poor prognosis of thyroid carcinoma (TC) and its molecular mechanisms are not fully understood. STRA6 is a multifunctional membrane protein widely expressed in embryonic and… read more here.
Keywords: progression via; thyroid carcinoma; ilk akt; progression ... See more keywords
STRA6 regulates tumor immune microenvironment and is a prognostic marker in BRAF-mutant papillary thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1076640
Abstract: Background BRAF mutation is one of the most common genetic alterations contributing to the initiation and progression of papillary thyroid carcinoma (PTC). However, the prognostic value of BRAF mutation for PTC is limited. Novel markers… read more here.
Keywords: ptc; braf; tumor immune; braf mutant ... See more keywords