Straightforward synthesis of 4,5-bifunctionalized 1,2-oxazinanes via Lewis acid promoted regio- and stereo-selective nucleophilic ring-opening of 3,6-dihydro-1,2-oxazine oxides
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.05.015
Abstract: Abstract Functionalized 1,2-oxazinanes are interesting and valuable heterocycles with potential applications in synthetic and medicinal chemistry. A straightforward strategy for quick access to unprecedented trans-4-hydroxyl-5-azido/cyano/amino 1,2-oxazinanes are developed: N-COR 3,6-dihydro- 1,2-oxazine oxides are prepared with… read more here.
Keywords: dihydro oxazine; oxazine oxides; straightforward synthesis; lewis acid ... See more keywords
Straightforward synthesis of novel substituted 1,3,4-thiadiazole derivatives in choline chloride-based deep eutectic solvent
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.01.057
Abstract: A one-pot, three-component route for the synthesis of novel 1,3,4-thiadiazole derivatives using a ketene S,S-acetal, a carbonyl compound and thiocarbohydrazide is described. The main advantages of this approach are high yields, short reaction times, simple… read more here.
Keywords: synthesis novel; straightforward synthesis; novel substituted; substituted thiadiazole ... See more keywords
Straightforward Synthesis of Single-Crystalline and Redox-Active Cr(II)-carboxylate MOFs.
Sign Up to like & getrecommendations! Published in 2018 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.8b00395
Abstract: We report on a facile and environmentally friendly synthetic approach for single-crystalline chromium(II) carboxylate metal-organic frameworks (i.e., Cr3(BTC)2·3H2O (1) and Cr(hfipbb)·H2O (2) at room temperature in water. Both MOFs can be easily dehydrated, affording single-crystalline… read more here.
Keywords: carboxylate; straightforward synthesis; synthesis single; redox ... See more keywords
Ru(0)-Catalyzed Straightforward Synthesis of Conjugated Tetraenes: An Approach using Two Internal Alkynes with 1,3-Butadiene
Sign Up to like & getrecommendations! Published in 2018 at "Organometallics"
DOI: 10.1021/acs.organomet.7b00801
Abstract: The Ru(0)-catalyzed straightforward synthesis of conjugated tetraenes has been achieved in up to 85% yield by coupling of 2 equiv of internal alkynes with 1,3-butadiene at room temperature. The stoichiometric reaction of [Ru(η4-cisoid-1,3-butadiene)(η4-1,5-COD)(NCMe)] with 2… read more here.
Keywords: synthesis conjugated; straightforward synthesis; internal alkynes; alkynes butadiene ... See more keywords
Straightforward synthesis of bench-stable heteroatom-centered difluoromethylated entities via controlled nucleophilic transfer from activated TMSCHF2.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00886f
Abstract: The commercially available and experimentally convenient (bp 65 °C) difluoromethyltrimethylsilane (TMSCHF2) is proposed as a valuable difluoromethylating transfer reagent for delivering the CHF2 moiety to various heteroatom-based electrophiles. Upon activation with an alkoxide, a conceptually… read more here.
Keywords: bench stable; transfer; synthesis bench; straightforward synthesis ... See more keywords