Straightforward synthesis of 4,5-bifunctionalized 1,2-oxazinanes via Lewis acid promoted regio- and stereo-selective nucleophilic ring-opening of 3,6-dihydro-1,2-oxazine oxides
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.05.015
Abstract: Abstract Functionalized 1,2-oxazinanes are interesting and valuable heterocycles with potential applications in synthetic and medicinal chemistry. A straightforward strategy for quick access to unprecedented trans-4-hydroxyl-5-azido/cyano/amino 1,2-oxazinanes are developed: N-COR 3,6-dihydro- 1,2-oxazine oxides are prepared with… read more here.
Keywords: dihydro oxazine; oxazine oxides; straightforward synthesis; lewis acid ... See more keywords
Straightforward synthesis of novel substituted 1,3,4-thiadiazole derivatives in choline chloride-based deep eutectic solvent
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.01.057
Abstract: A one-pot, three-component route for the synthesis of novel 1,3,4-thiadiazole derivatives using a ketene S,S-acetal, a carbonyl compound and thiocarbohydrazide is described. The main advantages of this approach are high yields, short reaction times, simple… read more here.
Keywords: synthesis novel; straightforward synthesis; novel substituted; substituted thiadiazole ... See more keywords
Straightforward Synthesis of Single-Crystalline and Redox-Active Cr(II)-carboxylate MOFs.
Sign Up to like & getrecommendations! Published in 2018 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.8b00395
Abstract: We report on a facile and environmentally friendly synthetic approach for single-crystalline chromium(II) carboxylate metal-organic frameworks (i.e., Cr3(BTC)2·3H2O (1) and Cr(hfipbb)·H2O (2) at room temperature in water. Both MOFs can be easily dehydrated, affording single-crystalline… read more here.
Keywords: carboxylate; straightforward synthesis; synthesis single; redox ... See more keywords
Ru(0)-Catalyzed Straightforward Synthesis of Conjugated Tetraenes: An Approach using Two Internal Alkynes with 1,3-Butadiene
Sign Up to like & getrecommendations! Published in 2018 at "Organometallics"
DOI: 10.1021/acs.organomet.7b00801
Abstract: The Ru(0)-catalyzed straightforward synthesis of conjugated tetraenes has been achieved in up to 85% yield by coupling of 2 equiv of internal alkynes with 1,3-butadiene at room temperature. The stoichiometric reaction of [Ru(η4-cisoid-1,3-butadiene)(η4-1,5-COD)(NCMe)] with 2… read more here.
Keywords: synthesis conjugated; straightforward synthesis; internal alkynes; alkynes butadiene ... See more keywords
Straightforward synthesis of bench-stable heteroatom-centered difluoromethylated entities via controlled nucleophilic transfer from activated TMSCHF2.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00886f
Abstract: The commercially available and experimentally convenient (bp 65 °C) difluoromethyltrimethylsilane (TMSCHF2) is proposed as a valuable difluoromethylating transfer reagent for delivering the CHF2 moiety to various heteroatom-based electrophiles. Upon activation with an alkoxide, a conceptually… read more here.
Keywords: bench stable; transfer; synthesis bench; straightforward synthesis ... See more keywords
Straightforward synthesis of diarylacetylenes from tetrachloroethylene using Kumada coupling reaction by Pd catalyst. Application to tri- and tetraarylethylenes
Sign Up to like & getrecommendations! Published in 2025 at "Bulletin of the Chemical Society of Japan"
DOI: 10.1093/bulcsj/uoaf025
Abstract: Pd-catalyzed Kumada coupling reaction of tetrachloroethylene and Grignard reagents was effective for the formation of diarylacetylenes as simple and convenient reaction, in which diarylacetylenes were successfully obtained in up to 82% yields and 14 examples… read more here.
Keywords: reaction; straightforward synthesis; kumada coupling; coupling reaction ... See more keywords