A Bayesian framework for molecular strain identification from mixed diagnostic samples
Sign Up to like & getrecommendations! Published in 2018 at "Inverse Problems"
DOI: 10.1088/1361-6420/aad7cd
Abstract: We provide a mathematical formulation and develop a computational framework for identifying multiple strains of microorganisms from mixed samples of DNA. Our method is applicable in public health domains where efficient identification of pathogens is… read more here.
Keywords: identification; bayesian framework; problem; strain identification ... See more keywords
VirStrain: a strain identification tool for RNA viruses
Sign Up to like & getrecommendations! Published in 2022 at "Genome Biology"
DOI: 10.1186/s13059-022-02609-x
Abstract: Viruses change constantly during replication, leading to high intra-species diversity. Although many changes are neutral or deleterious, some can confer on the virus different biological properties such as better adaptability. In addition, viral genotypes often… read more here.
Keywords: tool; virstrain strain; rna viruses; strain identification ... See more keywords