Strain improvement of industrially important microorganisms based on resistance to toxic metabolites and abiotic stress
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.201600710
Abstract: Improvement of the biosynthetic capabilities of industrially relevant microbes to produce desired metabolites in higher quantities is one of the important topics of modern biotechnology. In this article, different strategies of improvement of mutated microbial… read more here.
Keywords: improvement; industrially important; improvement industrially; important microorganisms ... See more keywords
Application of In Vitro Transposon Mutagenesis to Erythromycin Strain Improvement in Saccharopolyspora erythraea.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6472-7_17
Abstract: Transposon mutagenesis is an invaluable technique in molecular biology for the creation of random mutations that can be easily identified and mapped. However, in the field of microbial strain improvement, transposon mutagenesis has scarcely been… read more here.
Keywords: transposon mutagenesis; biology; transposon; strain improvement ... See more keywords
Agrobacterium strains and strain improvement: Present and outlook.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology advances"
DOI: 10.1016/j.biotechadv.2020.107677
Abstract: Almost 40 years ago the first transgenic plant was generated through Agrobacterium tumefaciens-mediated transformation, which, until now, remains the method of choice for gene delivery into plants. Ever since, optimized Agrobacterium strains have been developed with… read more here.
Keywords: transformation; agrobacterium; agrobacterium strains; strain improvement ... See more keywords
Unlocking a new target for streptomycetes strain improvement
Sign Up to like & getrecommendations! Published in 2020 at "Synthetic and Systems Biotechnology"
DOI: 10.1016/j.synbio.2020.02.001
Abstract: Bacteria of the Streptomyces genus are well-known producers of secondary metabolites of high medical value. They contributed nearly 60% of current antibiotics (i.e., vancomycin, daptomycin and tetracycline), as well as antifungals, antiparasitics (avermectins), anticancer drugs… read more here.
Keywords: production; metabolism; secondary metabolism; acetyl coa ... See more keywords
Droplet-based microfluidics as a future tool for strain improvement in lactic acid bacteria.
Sign Up to like & getrecommendations! Published in 2018 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fny258
Abstract: Strain development is frequently used to improve the performance and functionality of industrially important microbes. As traditional mutagenesis screen is especially utilized by the food industry to improve strains used in food fermentation, high-throughput and… read more here.
Keywords: based microfluidics; droplet based; acid bacteria; strain improvement ... See more keywords
Metabolomics-driven strain improvement: A mini review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1057709
Abstract: In recent years, mass spectrometry-based metabolomics has been established as a powerful and versatile technique for studying cellular metabolism by comprehensive analysis of metabolites in the cell. Although there are many scientific reports on the… read more here.
Keywords: improvement; strain improvement; mini review; metabolomics driven ... See more keywords