Strain release in GaN epitaxy on 4° off-axis 4H-SiC.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced materials"
DOI: 10.1002/adma.202201169
Abstract: The hybrid field-effect transistor (HyFET) superior for power electronic applications can be created by harnessing the merits of two representative wide-bandgap semiconductors, GaN and SiC. Yet, the incompactness in the epitaxy techniques hinders the development… read more here.
Keywords: release gan; axis sic; strain release; epitaxy axis ... See more keywords
Highly Efficient and Stable Strain-Release Radioiodination for Thiol Chemoselective Bioconjugation.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.7b00790
Abstract: We report a novel thiol selective radioiodination method based on strain-release reaction. A new heterobifunctional radioiodination agent which has very good thiol selectivity and excellent stability with high radiolabeling yield was synthesized, characterized, and applied… read more here.
Keywords: thiol; highly efficient; strain release; radioiodination ... See more keywords
Aza-ortho-Quinone Methide Promoted Strain-Release-Driven Conversion of Azabicyclo[1.1.0]butanes into Functionalized Azetidines.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c03577
Abstract: A strategy for activating azabicyclo[1.1.0]butane (ABB) with in situ generated aza-ortho-quinone methide, promoted by HFIP, is reported. This unified activation, vis-à-vis strain-release-driven N/C3-functionalization, features a new means to prepare functionalized azetidines from ABB. Additionally, the… read more here.
Keywords: strain release; quinone methide; methide promoted; ortho quinone ... See more keywords
Double Strain-Release [2π+2σ]-Photocycloaddition.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c11563
Abstract: In pursuit of potent pharmaceutical candidates and to further improve their chemical traits, small ring systems can serve as a potential starting point. Small ring units have the additional merit of loaded strain at their… read more here.
Keywords: strain release; double strain; photocycloaddition; release photocycloaddition ... See more keywords
Strain-Release-Driven Synthesis of Pentafluorosulfanylated Four-Membered Rings under Energy Transfer Photocatalysis.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.5c07138
Abstract: Methods to prepare SF5-containing molecules are of significant interest, as the pentafluorosulfanyl (SF5) group imparts unique chemical and physical properties─such as high electronegativity, and thermal stability─that are valuable in pharmaceuticals, agrochemicals, and materials science. The… read more here.
Keywords: strain release; energy transfer; four membered;
Strain-release driven reactivity of a chiral SuFEx reagent provides stereocontrolled access to sulfinamides, sulfonimidamides, and sulfoximines
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-51224-w
Abstract: Efforts aimed at enriching the chemical and structural diversity of small molecules have invigorated synthetic exploration in the last two decades. Spatially defined molecular functionality serves as the foundation to construct unique chemical space to… read more here.
Keywords: strain release; chiral sufex; chemical space; sufex reagent ... See more keywords
Strain-release arylations for the bis-functionalization of azetidines.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc07053c
Abstract: The addition of nucleophilic organometallic species onto in situ generated azabicyclobutanes enables the selective formation of 3-arylated azetidine intermediates through strain-release. Single pot strategies were further developed for the N-arylation of resulting azetidines, employing either… read more here.
Keywords: strain release; release arylations; arylations bis; functionalization azetidines ... See more keywords
Strain-release enables access to carbonyl conjugated allylic diborons and alkenyl boronates having multiple contiguous stereocenters in a one-pot process
Sign Up to like & getrecommendations! Published in 2024 at "Chemical Science"
DOI: 10.1039/d4sc06514j
Abstract: Allylic diboronates are highly valuable reagents in organic synthesis. Existing methods predominantly yield alkyl-substituted allylic diboronates, while the incorporation of electrophilic carbonyl groups conjugated to these allylic systems remains unknown. We present a strain-release promoted… read more here.
Keywords: strain release; carbonyl; carbonyl conjugated; one pot ... See more keywords
Strain-release driven spirocyclization of bicyclo[1.1.0]butanes: access to 6,7-diazaspiro[3.4]octanes
Sign Up to like & getrecommendations! Published in 2025 at "Chemical Science"
DOI: 10.1039/d5sc03141a
Abstract: The use of ring strain in bicyclo[1.1.0]butanes (BCBs) to facilitate organic transformations is a powerful strategy in organic synthesis. However, their application to the synthesis of spirocyclic scaffolds has remained challenging. Spirocyclobutanes have attracted considerable… read more here.
Keywords: strain release; diazaspiro octanes; bicyclo butanes; spirocyclization ... See more keywords
Recent Advances in Strain-Release Functionalization of [1.1.1]Propellanes Using Organometallic Reagents
Sign Up to like & getrecommendations! Published in 2025 at "Synlett"
DOI: 10.1055/a-2669-6239
Abstract: The highly strained bicyclic hydrocarbon bicyclo[1.1.1]propellane has emerged as a versatile scaffold in synthetic organic and medicinal chemistry due to the remarkable structural reactivity of its central bond between the two bridgehead carbons. Over the… read more here.
Keywords: strain release; chemistry; organometallic reagents; recent advances ... See more keywords
Strain release through hydrogen bond–mediated layer twisting
Sign Up to like & getrecommendations! Published in 2025 at "Science Advances"
DOI: 10.1126/sciadv.ady6869
Abstract: Strain engineering, enabling the precise control over structure and functional properties, is a key strategy for the design of advanced materials. However, the mechanisms governing strain evolution and release at the nanoscale remain largely unexplored.… read more here.
Keywords: strain; hydrogen; layer twisting; strain release ... See more keywords