Strain-Specific Propagation by an Amyloid-Beta Dodecamer
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1962
Abstract: Soluble oligomers of the amyloid-β (Aβ) peptide have emerged as the primary neurotoxic agents in Alzheimer disease (AD). Increasing evidence implicates aggregates of Aβ to propagate towards fibrils in a strain-specific manner. Morphological differences observed… read more here.
Keywords: propagation; seed; dodecamer; specific propagation ... See more keywords
Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators
Sign Up to like & getrecommendations! Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2020.10.020
Abstract: (Cell 180, 1018–1032.e1–e16; March 5, 2020) Our paper reported the development of programmable RNA-based sensors for detection of specific mutations. Figure 6D presents application of the sensors to distinguish between different strains of Zika virus.… read more here.
Keywords: figure; rna; paper; specific snipr ... See more keywords
The impact of strain-specific immunity on Lyme disease incidence is spatially heterogeneous.
Sign Up to like & getrecommendations! Published in 2017 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2017.08.015
Abstract: Lyme disease, caused by the bacterium Borrelia burgdorferi, is the most common tick-borne infection in the US. Recent studies have demonstrated that the incidence of human Lyme disease would have been even greater were it… read more here.
Keywords: specific immunity; lyme disease; strain specific; disease ... See more keywords
RNase 1, 2, 5 & 8 role in innate immunity: Strain specific antimicrobial activity.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.06.001
Abstract: The increase in microbial resistance to conventional antimicrobial agents is driving research for the discovery of new antibiotics and antifungal agents. The greatest challenge in this endeavor is to find antimicrobial agents with broad antimicrobial… read more here.
Keywords: specific antimicrobial; antimicrobial activity; activity rnase; strain specific ... See more keywords
Evidence for strain-specific virulence of Trichomonas gallinae in African columbiformes
Sign Up to like & getrecommendations! Published in 2022 at "Parasitology"
DOI: 10.1017/s0031182022001652
Abstract: Abstract Abstract Infection by parasites or pathogens can have marked physiological impacts on individuals. In birds, infection may affect moult and feather growth, which is an energetically demanding time in the annual cycle. Previous work… read more here.
Keywords: infection; strain specific; trichomonas gallinae; strain ... See more keywords
Genetic variation in IL-4 activated tissue resident macrophages determines strain-specific synergistic responses to LPS epigenetically
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-56379-8
Abstract: How macrophages in the tissue environment integrate multiple stimuli depends on the genetic background of the host, but this is still poorly understood. We investigate IL-4 activation of male C57BL/6 and BALB/c strain specific in… read more here.
Keywords: resident macrophages; strain specific; genetic variation; tissue resident ... See more keywords
In vivo microscopic voxel-based morphometry with a brain template to characterize strain-specific structures in the mouse brain
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-00148-1
Abstract: Hundreds of inbred mouse strains are established for use in a broad spectrum of basic research fields, including genetics, neuroscience, immunology, and cancer. Inbred mice exhibit identical intra-strain genetics and divergent inter-strain phenotypes. The cognitive… read more here.
Keywords: vivo microscopic; strain specific; voxel based; strain ... See more keywords
Genetic variability of the U5 and downstream sequence of major HIV-1 subtypes and circulating recombinant forms
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-70083-1
Abstract: The critical role of the regulatory elements at the 5′ end of the HIV-1 genome in controlling the life cycle of HIV-1 indicates that this region significantly influences virus fitness and its biological properties. In… read more here.
Keywords: hiv; variability; strain specific; strain ... See more keywords
Development of strain specific simple sequence repeats and assessment of genetic diversity in Erwinia amylovora from marker selection to phylogenetic analysis
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-15530-7
Abstract: Erwinia amylovora is a highly destructive phytopathogenic bacterium that causes fire blight in Rosaceae plants, particularly apple and pear trees. Due to its status as a quarantine organism in many countries, extensive epidemiological and genotypic… read more here.
Keywords: erwinia amylovora; simple sequence; analysis; specific simple ... See more keywords
Comparative genomic analysis of hydrogen peroxide and nitric oxide metabolic pathways in Limosilactobacillus fermentum.
Sign Up to like & getrecommendations! Published in 2025 at "Scientific reports"
DOI: 10.1038/s41598-025-29368-6
Abstract: Limosilactobacillus fermentum strains influence human health through distinct metabolic pathways; however, the genetic basis of these strain-specific functions remains unclear. This study investigated phenotypic divergence between two L. fermentum strains isolated from the human oral… read more here.
Keywords: metabolic pathways; strain specific; nitric oxide; limosilactobacillus fermentum ... See more keywords
Strain-specific variations in the culture of chicken primordial germ cells
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-93777-w
Abstract: Efficient long-term cultivation of chicken primordial germ cells (cPGCs) is essential for various avian research and biotechnology applications. Our study aimed to address the challenge of inconsistent culture success by investigating strain-specific variations and optimizing… read more here.
Keywords: chicken primordial; culture; germ; strain specific ... See more keywords