Two New 5-Oxomilbemycins Possessing an Unusual 3,27-Epoxy Bond from the Genetically Engineered Strain Streptomyces bingchenggensis BCJ60
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DOI: 10.1007/s10600-021-03339-5
Abstract: Two undescribed milbemycin derivatives, milbemycin P (1) and milbemycin Q (2), were isolated from a culture of the genetically engineered strain Streptomyces bingchenggensis BCJ60. Their structures were elucidated through the interpretation of NMR and HR-ESI-MS… read more here.
Keywords: strain streptomyces; engineered strain; genetically engineered; streptomyces bingchenggensis ... See more keywords
Acyltransferase Domain Swapping for the Production of Tenvermectin B Metabolites in Genetically Engineered Strain Streptomyces avermitilis HU02.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c04482
Abstract: Tenvermectins A and B (TVMs A and B) are hybrid natural compounds of avermectins and milbemycins with enhanced insecticidal activity. Aiming at obtaining a strain for the production of the higher activity metabolite-TVM-B as a… read more here.
Keywords: strain streptomyces; avermitilis hu02; strain; production ... See more keywords
Two new milbemycin derivatives from a genetically engineered strain Streptomyces bingchenggensis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2020.1783656
Abstract: Abstract Two new milbemycin derivatives, milbemycin M (1) and milbemycin N (2), were isolated from the culture of a genetically engineered strain Streptomyces bingchenggensis BCJ60. Their structures were elucidated through the interpretation of NMR and… read more here.
Keywords: genetically engineered; two new; engineered strain; new milbemycin ... See more keywords
The Antitumor Antibiotics Complex of Aureolic Acids from the Marine Sediment-associated Strain of Streptomyces sp. KMM 9048
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DOI: 10.1177/1934578x1701200427
Abstract: A new antibiotic complex of six aureolic acids was isolated from the marine sediment-associated strain Streptomyces sp. KMM 9048. Four of the compounds (3–6) were found to be similar but not identical to the known… read more here.
Keywords: streptomyces kmm; aureolic acids; associated strain; strain streptomyces ... See more keywords
Cytotoxic Minor Piericidin Derivatives from the Actinomycete Strain Streptomyces psammoticus SCSIO NS126
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DOI: 10.3390/md19080428
Abstract: The mangrove-sediment-derived actinomycete strain Streptomyces psammoticus SCSIO NS126 was found to have productive piericidin metabolites featuring anti-renal cell carcinoma activities. In this study, in order to explore more diverse piericidin derivatives, and therefore to discover… read more here.
Keywords: piericidin derivatives; streptomyces psammoticus; actinomycete strain; piericidin ... See more keywords