Inhibiting the β1integrin subunit increases the strain threshold for neuronal dysfunction under tensile loading in collagen gels mimicking innervated ligaments.
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DOI: 10.1007/s10237-022-01565-6
Abstract: Stretch injury of the facet capsular ligament is a cause of neck pain, inducing axonal injury, neuronal hyperexcitability, and upregulation of pain neuromodulators. Although thresholds for pain and collagen reorganization have been defined and integrins… read more here.
Keywords: collagen; neuronal dysfunction; strain threshold; tensile loading ... See more keywords