FANCA Promotes DNA Double-Strand Break Repair by Catalyzing Single-Strand Annealing and Strand Exchange.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.06.030
Abstract: FANCA is a component of the Fanconi anemia (FA) core complex that activates DNA interstrand crosslink repair by monoubiquitination of FANCD2. Here, we report that purified FANCA protein catalyzes bidirectional single-strand annealing (SA) and strand… read more here.
Keywords: annealing strand; strand; single strand; strand annealing ... See more keywords
Structure of polymerized type V pilin reveals assembly mechanism involving protease-mediated strand exchange
Sign Up to like & getrecommendations! Published in 2020 at "Nature Microbiology"
DOI: 10.1038/s41564-020-0705-1
Abstract: Bacterial adhesion is a general strategy for host–microbe and microbe–microbe interactions. Adhesive pili are essential for colonization, biofilm formation, virulence and pathogenesis of many environmental and pathogenic bacteria 1 , 2 . Members of the… read more here.
Keywords: protease mediated; protease; assembly mechanism; mediated strand ... See more keywords
Mechanism of strand exchange from RecA-DNA synaptic and D-loop structures
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2820-9
Abstract: The strand-exchange reaction is central to homologous recombination. It is catalysed by the RecA family of ATPases, which form a helical filament with single-stranded DNA (ssDNA) and ATP. This filament binds to a donor double-stranded… read more here.
Keywords: dsdna; microscopy; dna; exchange ... See more keywords
RadD is a RecA-dependent accessory protein that accelerates DNA strand exchange
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac041
Abstract: Abstract In rapidly growing cells, with recombinational DNA repair required often and a new replication fork passing every 20 min, the pace of RecA-mediated DNA strand exchange is potentially much too slow for bacterial DNA… read more here.
Keywords: dna strand; strand exchange; radd; protein ... See more keywords
The second messenger cyclic di‐AMP negatively regulates the expression of Mycobacterium smegmatis recA and attenuates DNA strand exchange through binding to the C‐terminal motif of mycobacterial RecA proteins
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Microbiology"
DOI: 10.1111/mmi.13991
Abstract: Cyclic di‐GMP and cyclic di‐AMP are second messengers produced by a wide variety of bacteria. They influence bacterial cell survival, biofilm formation, virulence and bacteria–host interactions. However, many of their cellular targets and biological effects… read more here.
Keywords: mycobacterium; cyclic amp; reca; dna strand ... See more keywords
Bacillus subtilis MutS Modulates RecA-Mediated DNA Strand Exchange Between Divergent DNA Sequences
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.00237
Abstract: The efficiency of horizontal gene transfer, which contributes to acquisition and spread of antibiotic resistance and pathogenicity traits, depends on nucleotide sequence and different mismatch-repair (MMR) proteins participate in this process. To study how MutL… read more here.
Keywords: sequence; dna strand; strand exchange; dna ... See more keywords