Molecular insights into RNA-binding properties of Escherichia coli–expressed RNA-dependent RNA polymerase of Antheraea mylitta cytoplasmic polyhedrosis virus
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Virology"
DOI: 10.1007/s00705-017-3412-3
Abstract: Antheraea mylitta cytoplasmic polyhedrosis virus (AmCPV) is responsible for morbidity of the Indian non-mulberry silkworm, A. mylitta. AmCPV belongs to the family Reoviridae and has 11 double-stranded (ds) RNA genome segments (S1-S11). Segment 2 (S2)… read more here.
Keywords: strand rna; rna; rna binding; polymerase ... See more keywords
Template requirements of Zika RNA polymerase during in vitro RNA synthesis from the 3'-end of virus minus-strand RNA.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.11.003
Abstract: As ZIKV continues to spread, many "unknowns" remain and research is needed to advance the understanding of this important pathogen. Viral RNA dependent-RNA polymerases (RdRp) are validated targets for inhibitors of the replication of several… read more here.
Keywords: minus strand; rna synthesis; strand rna; rna ... See more keywords
N-protein-RNA interaction is a drug target in a negative strand RNA virus
Sign Up to like & getrecommendations! Published in 2021 at "Virus Research"
DOI: 10.1016/j.virusres.2021.198298
Abstract: The negative strand RNA virus family contains many human pathogens. Finding new antiviral drug targets against this class of human pathogens is one of the significant healthcare needs. Nucleocapsid proteins of negative strand RNA viruses… read more here.
Keywords: strand rna; rna; drug; strand ... See more keywords
Positive‐strand RNA viruses—a Keystone Symposia report
Sign Up to like & getrecommendations! Published in 2023 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14957
Abstract: Positive‐strand RNA viruses have been the cause of several recent outbreaks and epidemics, including the Zika virus epidemic in 2015, the SARS outbreak in 2003, and the ongoing SARS‐CoV‐2 pandemic. On June 18–22, 2022, researchers… read more here.
Keywords: report; rna viruses; strand rna; positive strand ... See more keywords
Constraints of Viral RNA Synthesis on Codon Usage of Negative-Strand RNA Virus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.01775-18
Abstract: Negative-strand RNA viruses (NSVs) include the most pathogenic viruses known. New methods to monitor their evolutionary trends are urgently needed for the development of antivirals and vaccines. The protein translation machinery of the host cell… read more here.
Keywords: rna synthesis; strand rna; codon usage; rna ... See more keywords
Crowning Touches in Positive-Strand RNA Virus Genome Replication Complex Structure and Function.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of virology"
DOI: 10.1146/annurev-virology-092920-021307
Abstract: Positive-strand RNA viruses, the largest genetic class of eukaryotic viruses, include coronaviruses and many other established and emerging pathogens. A major target for understanding and controlling these viruses is their genome replication, which occurs in… read more here.
Keywords: virology; replication; rna; positive strand ... See more keywords
Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1010423
Abstract: Plus-strand RNA viruses are the largest group of viruses. Many are human pathogens that inflict a socio-economic burden. Interestingly, plus-strand RNA viruses share remarkable similarities in their replication. A hallmark of plus-strand RNA viruses is… read more here.
Keywords: plus strand; replication; rna; virus ... See more keywords
Recombination in Positive-Strand RNA Viruses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.870759
Abstract: RNA recombination is a major driver of genetic shifts tightly linked to the evolution of RNA viruses. Genomic recombination contributes substantially to the emergence of new viral lineages, expansion in host tropism, adaptations to new… read more here.
Keywords: recombination; rna; recombination positive; positive strand ... See more keywords