Folding of single-stranded circular DNA into rigid rectangular DNA accelerates its cellular uptake.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c9nr08695a
Abstract: Despite the importance of the interaction between DNA and cells for its biological activity, little is known about exactly how DNA interacts with cells. To elucidate the relationship between the structural properties of DNA and… read more here.
Keywords: single stranded; stranded circular; circular dna; dna ... See more keywords
Synthesis and cloning of long repeat sequences using single-stranded circular DNA
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1115159
Abstract: Non-coding repeat expansion causes several neurodegenerative diseases, such as fragile X syndrome, amyotrophic lateral sclerosis/frontotemporal dementia, and spinocerebellar ataxia (SCA31). Such repetitive sequences must be investigated to understand disease mechanisms and prevent them, using novel… read more here.
Keywords: single stranded; long repeat; repeat; sequences using ... See more keywords
Single-stranded circular DNA theranostics
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.66466
Abstract: The past decade has witnessed the blossom of nucleic acid therapeutics and diagnostics (theranostics). Unlike conventional small molecule medicines or protein biologics, nucleic acid theranostics have characteristic features such as the intrinsic ability as “information… read more here.
Keywords: single stranded; stranded circular; circular dna; dna ... See more keywords