Specific and robust hybridization based on double-stranded nucleic acids with single-base resolution.
Sign Up to like & getrecommendations! Published in 2022 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2022.339568
Abstract: Nucleic acid hybridization plays a critical role in medical diagnostics and nanotechnology, but its selectivity and robustness remain to be improved. Here, focusing on double-stranded nucleic acid-based hybridization, we present a series of related strategies.… read more here.
Keywords: hybridization; double stranded; nucleic acids; stranded nucleic ... See more keywords
Visualizing single-stranded nucleic acids in solution
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkw1297
Abstract: Abstract Single-stranded nucleic acids (ssNAs) are ubiquitous in many key cellular functions. Their flexibility limits both the number of high-resolution structures available, leaving only a small number of protein–ssNA crystal structures, while forcing solution investigations… read more here.
Keywords: single stranded; nucleic acids; visualizing single; solution ... See more keywords