Keeping the strands together: Rad53 regulation of fork symmetry promotes replication stability
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DOI: 10.1002/bies.202200141
Abstract: DNAreplicationduringthesynthesis(S-)phaseofthecellcycleisakey step in cell proliferation. DNA replication fidelity and cell cycle checkpoints ensure that transient DNA damage is not converted into stable mutations.Thesedirectlinkstocellproliferationandmutationalavoid-ancemakeDNAreplicationcheckpointsimportanttogenomestability. He and Zhang’s Hypothesis explores how DNA replication complexes are maintained during… read more here.
Keywords: strands together; dna; replication; fork ... See more keywords