Strategies, design, and chemistry in siRNA delivery systems.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2019.05.004
Abstract: Emerging therapeutics that utilize RNA interference (RNAi) have the potential to treat broad classes of diseases due to their ability to reversibly silence target genes. In August 2018, the FDA approved the first siRNA therapeutic,… read more here.
Keywords: sirna delivery; delivery; chemistry; delivery systems ... See more keywords
Strategies for the design of bright upconversion nanoparticles for bioanalytical applications
Sign Up to like & getrecommendations! Published in 2018 at "Optical Materials"
DOI: 10.1016/j.optmat.2018.04.015
Abstract: Abstract In recent years upconversion nanoparticles (UCNPs) received great attention because of their outstanding optical properties. Especially in bioanalytical applications this class of materials can overcome limitations of common probes like high background fluorescence or… read more here.
Keywords: design bright; upconversion nanoparticles; bright upconversion; bioanalytical applications ... See more keywords
HDAC Inhibitors: Innovative Strategies for Their Design and Applications
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030715
Abstract: Histone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are involved in gene transcription and regulation, cell proliferation, differentiation, migration, and death, as well as angiogenesis. Particularly, disorders of the HDACs expression are… read more here.
Keywords: design applications; inhibitors innovative; hdac inhibitors; innovative strategies ... See more keywords