Strategies for designing proteolysis targeting chimaeras (PROTACs)
Sign Up to like & getrecommendations! Published in 2022 at "Medicinal Research Reviews"
DOI: 10.1002/med.21877
Abstract: Proteolysis targeting chimaeras (PROTACs) is a cutting edge and rapidly growing technique for new drug discovery and development. Currently, the largest challenge in the molecular design and drug development of PROTACs is efficient identification of… read more here.
Keywords: protacs; chimaeras protacs; proteolysis targeting; targeting chimaeras ... See more keywords
Strategies in the designing of prodrugs, taking into account the antiviral and anticancer compounds.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.02.011
Abstract: Prodrugs are a wide group of substances of low or no pharmacological activity. The search for prodrugs is aimed at obtaining drugs characterized by better pharmacokinetic properties, pharmaceutical availability and selective activity of the active… read more here.
Keywords: designing prodrugs; taking account; strategies designing; account antiviral ... See more keywords
Strategies for designing organic fluorescent probes for biological imaging of reactive carbonyl species.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Society reviews"
DOI: 10.1039/c8cs00956b
Abstract: Reactive carbonyl species (RCS) are involved not only in diverse physiological pathways but also in various pathological processes, including Alzheimer's disease, diabetes, cardiovascular disease, and other malignant diseases. Therefore, it is essential to develop a… read more here.
Keywords: reactive carbonyl; strategies designing; designing organic; carbonyl species ... See more keywords
Emerging Topochemical Strategies for Designing Two-Dimensional Energy Materials
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DOI: 10.3390/mi12080867
Abstract: The unique properties of two-dimensional (2D) materials make them increasingly attractive in various fields, especially for energy harvesting, conversion, or storage. Simultaneously, numerous synthetic methods have been rapidly developed. Recently, topochemical strategies were demonstrated, and… read more here.
Keywords: energy; strategies designing; two dimensional; designing two ... See more keywords