Manufacturing strategies to develop amorphous solid dispersions: An overview.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of drug delivery science and technology"
DOI: 10.1016/j.jddst.2019.101459
Abstract: Since the past several decades, poor water solubility of existing and new drugs in the pipeline have remained a challenging issue for the pharmaceutical industry. Literature describes several approaches to improve the overall solubility, dissolution… read more here.
Keywords: develop amorphous; manufacturing strategies; solid dispersions; amorphous solid ... See more keywords
Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.1c00381
Abstract: This review presents a robust strategy to design photosensitizers (PSs) for various species. Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the use of light combined with a light-activated chemical, referred to as… read more here.
Keywords: photosensitizers enhanced; photodynamic therapy; develop innovative; therapy ... See more keywords
Recent strategies to develop pH-sensitive injectable hydrogels.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01519f
Abstract: "Smart" biomaterials that are responsive to pathological abnormalities are an appealing class of therapeutic platforms for the development of personalized medications. The development of such therapeutic platforms requires novel techniques that could precisely deliver therapeutic… read more here.
Keywords: therapeutic platforms; recent strategies; development; strategies develop ... See more keywords
Multiple Strategies to Develop Small Molecular KRAS Directly Bound Inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28083615
Abstract: KRAS gene mutation is widespread in tumors and plays an important role in various malignancies. Targeting KRAS mutations is regarded as the “holy grail” of targeted cancer therapies. Recently, multiple strategies, including covalent binding strategy,… read more here.
Keywords: develop small; multiple strategies; strategies develop; small molecular ... See more keywords
Strategies to Develop a Mucosa-Targeting Vaccine against Emerging Infectious Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14030520
Abstract: Numerous pathogenic microbes, including viruses, bacteria, and fungi, usually infect the host through the mucosal surfaces of the respiratory tract, gastrointestinal tract, and reproductive tract. The mucosa is well known to provide the first line… read more here.
Keywords: develop mucosa; infectious diseases; strategies develop; mucosal ... See more keywords