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Published in 2021 at "ChemMedChem"
DOI: 10.1002/cmdc.202100033
Abstract: AR plays a crucial role in the occurrence and development of prostate cancer (PCa) and its signaling pathway remains active in castration-resistant prostate cancer (CRPC) patients. The drug resistance of current clinical used antiandrogens is…
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Keywords:
protein;
improving strategies;
strategies development;
downregulation ... See more keywords
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Published in 2019 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2019.09.005
Abstract: Proteomic analysis can be a critical bottleneck in cellular characterization. The current paradigm relies primarily on mass spectrometry of peptides and affinity reagents (i.e., antibodies), both of which require a priori knowledge of the sample.…
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Keywords:
protein;
generation protein;
strategies development;
protein sequencing ... See more keywords
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Published in 2018 at "Drug research"
DOI: 10.1055/a-0582-9372
Abstract: The science of formulation involving cosmetic ingredients has always been a challenge since the release of active components greatly depends upon the carrier system involved and the selectivity of skin barrier. The principle obstacle of…
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Keywords:
delivery nanotechnology;
delivery;
strategies development;
nanotechnology ... See more keywords
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Published in 2021 at "Polymers"
DOI: 10.3390/polym13040624
Abstract: Synthetic polypeptides and polymer-peptide hybrid materials have been successfully implemented in an array of biomedical applications owing to their biocompatibility, biodegradability and ability to mimic natural proteins. In addition, these materials have the capacity to…
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Keywords:
polypeptides polymer;
synthetic polypeptides;
responsive synthetic;
polymer peptide ... See more keywords