Articles with "strategies discovery" as a keyword



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Contemporary medicinal-chemistry strategies for discovery of blood coagulation factor Xa inhibitors

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Published in 2019 at "Expert Opinion on Drug Discovery"

DOI: 10.1080/17460441.2019.1626821

Abstract: ABSTRACT Introduction: Thrombosis is a common causal pathology for stroke, acute coronary syndrome and venous thromboembolism disorders, which are the leading cause of death worldwide. Anticoagulants have exhibited a crucial role in the prevention and… read more here.

Keywords: fxa inhibitors; medicinal chemistry; chemistry; strategies discovery ... See more keywords