Strategies Employed for the Development of PARP Inhibitors.
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DOI: 10.1007/978-1-4939-6993-7_18
Abstract: This chapter describes the approaches taken in the development of the first PARP inhibitor to enter clinical trial, rucaparib (now called Rubraca), in 2003. We describe the general principles of crystal-based drug design, the purification… read more here.
Keywords: parp inhibitors; employed development; parp; development parp ... See more keywords
Articulatory compensation strategies employed by an aglossic speaker
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DOI: 10.1121/1.5014671
Abstract: We are employing real-time MRI to probe the speech production patterns of a speaker with congenital aglossia, a rare syndrome in which an individual is born without a tongue. The speaker being studied has only… read more here.
Keywords: speaker; employed aglossic; tongue; articulatory compensation ... See more keywords
Written Corrective Feedback Strategies Employed by University English Lecturers: A Teacher Cognition Perspective
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DOI: 10.25384/sage.c.5055808.v1
Abstract: Examining EFL (English as a foreign language) teachers’ beliefs and cognition has become an essential area of research as teachers are seen as active decision makers. This study addresses teachers’... read more here.
Keywords: corrective feedback; feedback strategies; strategies employed; cognition ... See more keywords
What is Normalization? The Strategies Employed in Top-Down and Bottom-Up Proteome Analysis Workflows
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DOI: 10.3390/proteomes7030029
Abstract: The accurate quantification of changes in the abundance of proteins is one of the main applications of proteomics. The maintenance of accuracy can be affected by bias and error that can occur at many points… read more here.
Keywords: analysis; top bottom; employed top; normalization strategies ... See more keywords