New strategies to identify protease substrates.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2020.09.009
Abstract: Proteome dynamics is governed by transcription, translation, and post-translational modifications. Limited proteolysis is an irreversible post-translational modification that generates multiple but unique proteoforms from almost every native protein. Elucidating these proteoforms and understanding their dynamics… read more here.
Keywords: medicine; protease substrates; strategies identify; protease ... See more keywords
Strategies to identify and dissect trade-offs in plants.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular ecology"
DOI: 10.1111/mec.16780
Abstract: Trade-offs between traits arise and reflect constraints imposed by the environment and physicochemical laws. Trade-off situations are expected to be highly relevant for sessile plants, which have to respond to changes in the environment to… read more here.
Keywords: offs plants; trade; strategies identify; identify dissect ... See more keywords
Computational strategies to identify new drug candidates against neuroinflammation.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220208095122
Abstract: The even more increasing application of computational approaches in these last decades has deeply modified the process of discovery and commercialization of new therapeutic entities. This is especially true in the field of neuroinflammation, in… read more here.
Keywords: identify new; neuroinflammation; computational strategies; new drug ... See more keywords