Strategies to Overcome Gender Bias in Maternity Nursing.
Sign Up to like & getrecommendations! Published in 2018 at "Nursing for women's health"
DOI: 10.1016/j.nwh.2018.07.001
Abstract: Male nurses and nursing students who work in maternity care often experience role strain, reverse discrimination, and gender bias. There are various strategies that clinical instructors, floor nurses, nursing school faculty, and nurse managers can… read more here.
Keywords: gender; maternity; maternity nursing; gender bias ... See more keywords
Oncolytic Herpes Simplex Virus Immunotherapy for Brain Tumors: Current Pitfalls and Emerging Strategies to Overcome Therapeutic Resistance
Sign Up to like & getrecommendations! Published in 2019 at "Oncogene"
DOI: 10.1038/s41388-019-0870-y
Abstract: Malignant tumors of the central nervous system (CNS) continue to be a leading cause of cancer-related mortality in both children and adults. Traditional therapies for malignant brain tumors consist of surgical resection and adjuvant chemoradiation;… read more here.
Keywords: immunotherapy; strategies overcome; herpes simplex; simplex virus ... See more keywords
Chemical strategies to overcome resistance against targeted anticancer therapeutics
Sign Up to like & getrecommendations! Published in 2020 at "Nature Chemical Biology"
DOI: 10.1038/s41589-020-0596-8
Abstract: Emergence of resistance is a major factor limiting the efficacy of molecularly targeted anticancer drugs. Understanding the specific mutations, or other genetic or cellular changes, that confer drug resistance can help in the development of… read more here.
Keywords: overcome resistance; chemical strategies; resistance; strategies overcome ... See more keywords
Melanoma immunotherapy: strategies to overcome pharmacological resistance
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2020.1745634
Abstract: ABSTRACT Introduction: Although checkpoint inhibitors have provided a breakthrough in how melanoma is treated, about half of patients still do not respond due to primary or acquired resistance. New strategies are, therefore, required to increase… read more here.
Keywords: melanoma; immunotherapy strategies; resistance; melanoma immunotherapy ... See more keywords
Strategies to overcome the diagnostic challenges of autoimmune hemolytic anemias.
Sign Up to like & getrecommendations! Published in 2023 at "Expert review of hematology"
DOI: 10.1080/17474086.2023.2216930
Abstract: INTRODUCTION The direct antiglobulin test (DAT) or Coombs test is the cornerstone of the diagnosis of autoimmune hemolytic anemia (AIHA). It can be performed by several methods with different sensitivity and specificity and enables the… read more here.
Keywords: dat; autoimmune hemolytic; test; strategies overcome ... See more keywords
Strategies to Overcome Bypass Mechanisms Mediating Clinical Resistance to EGFR Tyrosine Kinase Inhibition in Lung Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-16-0105
Abstract: The vast majority of patients with metastatic lung cancers who initially benefit from EGFR-targeted therapies eventually develop resistance. An increasing understanding of the number and complexity of resistance mechanisms highlights the challenge of treating tumors… read more here.
Keywords: overcome bypass; resistance; cancer; strategies overcome ... See more keywords
Combination strategies to overcome resistance to the BCL2 inhibitor venetoclax in hematologic malignancies
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01614-z
Abstract: Venetoclax has been approved by the United States Food and Drug Administration since 2016 as a monotherapy for treating patients with relapsed/refractory chronic lymphocytic leukemia having 17p deletion. It has led to a breakthrough in… read more here.
Keywords: venetoclax; overcome resistance; hematologic malignancies; resistance ... See more keywords
Strategies to Overcome Failures in T-Cell Immunotherapies by Targeting PI3K-δ and –γ
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.718621
Abstract: PI3K-δ and PI3K-γ are critical regulators of T-cell differentiation, senescence, and metabolism. PI3K-δ and PI3K-γ signaling can contribute to T-cell inhibition via intrinsic mechanisms and regulation of suppressor cell populations, including regulatory T-cells and myeloid… read more here.
Keywords: pi3k; failures cell; pi3k pi3k; overcome failures ... See more keywords
Strategies to overcome CAR-T cell resistance in clinical work: A single-institute experience
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.929221
Abstract: The emergence of chimeric antigen receptor (CAR) T cell therapy has shifted the paradigm of malignant tumor treatment, especially the advent of CD19-directed CAR-T cell therapy for the treatment of relapsed/refractory (R/R) B-cell malignancies. Although… read more here.
Keywords: cell; cell therapy; car; strategies overcome ... See more keywords
Strategies to overcome DC dysregulation in the tumor microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.980709
Abstract: Dendritic cells (DCs) play a key role to modulate anti-cancer immunity in the tumor microenvironment (TME). They link innate to adaptive immunity by processing and presenting tumor antigens to T cells thereby initiating an anti-tumor… read more here.
Keywords: tumor microenvironment; overcome dysregulation; strategies overcome; dysregulation tumor ... See more keywords
Therapeutic Strategies to Overcome Fibrotic Barriers to Nanomedicine in the Pancreatic Tumor Microenvironment
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15030724
Abstract: Simple Summary Pancreatic cancer is difficult to treat. Novel treatment strategies are urgently needed to improve the survival rate, which is approximately 10% five years after diagnosis. The use of nanomedicines, which are formulated within… read more here.
Keywords: nanomedicine pancreatic; pancreatic cancer; fibrotic barriers; strategies overcome ... See more keywords